Premier League Betting Odds & Predictions – Matchday 28

Odds & predictions from matchday 28 in the Premier League

Stuart Dallas / Leeds United ©IMAGO/Shutterstock 04/10/2018

We have reached the business end of the 2021-22 Premier League season, with matchday 28 of 38 taking place this weekend. We have another fascinating round of top-tier fixtures to look forward to, starting with the Leicester City vs Leeds United encounter on Saturday afternoon.

In the evening on Saturday, Liverpool welcome West Ham United to Anfield, while Watford and Arsenal clash at Vicarage Road on Sunday. The standout fixture is Sunday afternoon’s battle at the Etihad Stadium between rivals Manchester City and Manchester United. Check out our Premier League matchday 28 betting preview.


Premier League Matchday 28: Best Betting Football Tips

Leicester City vs. Leeds United: EPL Betting Tip

The Premier League weekend gets up and running when Leicester welcome Leeds to the King Power Stadium. Jesse Marsch will take charge of his first United game after Marcelo Bielsa’s departure from Elland Road. Can the American get off to a winning start?

The pressure has been on Brendan Rodgers lately, as Leicester are in the bottom half of the Premier League table after a tough season so far. However, they have won three of their last four in all competitions. Last time out, City claimed a much-needed 2-0 win at Burnley.

Our betting prediction:
Jamie Vardy to score first

Bet at 22Bet


(odds taken 2010 GMT, Friday 4 March)


Leeds are in freefall, taking just one point from their last six Premier League games. Since battling to a 3-3 draw with Aston Villa in early February, United have suffered four league losses on the spin, conceding 17 goals in the process.

This will be a tough first assignment for Marsch, and we fancy Leicester to build on the Burnley win by picking up three points at home on Saturday. The home victory is priced at 4/5.

Leicester City 4/5
Draw 3/1
Leeds United 3/1
* Bookmaker Unibet
Odds: 4/5 odds taken 1403 GMT, Friday 4 March


Liverpool vs. West Ham United: Best Premier League Betting Predictions

On Saturday evening, Liverpool and West Ham meet in a tasty matchup at Anfield. The Hammers are having another excellent season and are in fine form, but the Reds head into this one as the clear favourites with the bookies.

Liverpool are unbeaten at home across all competitions since losing to Fulham in a Premier League game back in March last year. The Merseysiders have won 11 league and cup fixtures in a row and have not lost since their final match of 2021.

West Ham are once again pushing for a UEFA Champions League place in the Premier League. Last time out in the league, Moyes’ men picked up a vital victory over fellow top-four hopefuls Wolverhampton Wanderers. However, they were beaten by Southampton in the FA Cup in midweek.

West Ham are in good spirits, but Liverpool should be too strong for the Londoners in this one. Back the hosts to win -1 at 4/5.

Liverpool 3/10
Draw 24/5
West Ham United 9/1
* Bookmaker Unibet
Odds: 4/5 odds taken 1410 GMT, Friday 4 March


Watford vs. Arsenal: EPL Betting Odds & Predictions

Struggling Watford welcome in-form Arsenal to Vicarage Road on Sunday. As the Hornets fight for Premier League survival, while the Gunners look to break into the top four, this is a massive match for both clubs.

Watford have had a pretty miserable season on their Premier League return, winning only five of 26 games. Roy Hodgson has guided the Hornets to just one win during his time in Hertfordshire, though his side did hold Man United to a goalless draw at Old Trafford last time out.

Arsenal are in outstanding form at present, winning seven of their last nine Premier League games. Since that gut-wrenching defeat to Man City on New Year’s Day, Mikel Arteta’s men have taken ten points from a possible 12.

Watford will be desperate for another positive result in their quest for survival, but we fancy the in-form Gunners to secure maximum points on their travels this weekend. Take a punt on the away team to be winning at half time and full time at 13/10.

Watford 27/5
Draw 3/1
Arsenal 11/20
* Bookmaker Unibet
Odds: 13/10 odds taken 1415 GMT, Friday 4 March


Manchester City vs. Manchester United: Best Premier League Betting Tips on Matchday 28

Last but not least, Man City and Man United lock horns at the Etihad Stadium in what promises to be a mouth-watering Manchester derby on Sunday afternoon. As you would expect, Pep Guardiola’s boys are the bookies’ favourites, but can United upset the Citizens?

Man City have responded with two away wins after their shock 3-2 league reverse to Tottenham Hotspur last month. The champions and current leaders have won a staggering 15 of their last 17 Premier League matches.

Man United have been tough to beat since Ralph Rangnick took over, with just Bruno Lage’s Wolves getting the better of the Red Devils in league action. Since then, United have won four and drawn four of eight. However, they were held to a disappointing home draw by lowly Watford in their last outing.

Despite a couple of minor wobbles of late, Man City have been in devastating form for months, and they should see off their neighbours in the derby. Back City to win -1 at the top odds of 21/20.

Manchester City 21/50
Draw 18/5
Manchester United 7/1
* Bookmaker Unibet
Odds: 21/20 odds taken 1425 GMT, Friday 4 March